Interactor 1: RRAGB (Q5VZM2)
Ras-related GTP-binding protein B (Rag B) (RagB) (EC 3.6.5.-)
Gene: RRAGB

Interactor 2: RRAGC (Q9HB90)
Ras-related GTP-binding protein C (Rag C) (RagC) (EC 3.6.5.-) (GTPase-interacting protein 2) (TIB929)
Gene: RRAGC

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.977

The method score is based on:

Property Details
Experiments 20381137, 28716898, 21981924, 22424946, 24337580, 25567906, 11073942, 33961781, 22980980, 25561175
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Gtr1_RagA~Gtr1_RagA
Common GO terms GO:0003924 - GTPase activity
GO:0005525 - GTP binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005764 - lysosome
and 11 others

more...

Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 374
Hs

1 399
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ Hs
+ Ce
+ Sp
+ Sc
+ Sc
+ Sc

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Last updated: 15 Jul 2024