HitPredict

Interactor 1: BSPRY (Q5W0U4)
B box and SPRY domain-containing protein
Gene: BSPRY

Interactor 2: RN135 (Q8IUD6)
E3 ubiquitin-protein ligase RNF135 (EC 2.3.2.27) (RIG-I E3 ubiquitin ligase) (REUL) (RING finger protein 135) (RING finger protein leading to RIG-I activation) (Riplet) (RING-type E3 ubiquitin transferase RNF135)
Gene: RNF135

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.65 1.00 0.811

The method score is based on:

Property Details
Experiments 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains PRY~SPRY, SPRY~SPRY
Common GO terms GO:0005737 - cytoplasm
GO:0016567 - protein ubiquitination
GO:0046872 - metal ion binding
GO:0061630 - ubiquitin protein ligase activity
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 402
Hs

1 432
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Last updated: 15 Jul 2024