HitPredict

Interactor 1: Q5XHF6 (Q5XHF6)
Rab40 GTPase (Rab40 protein) (Uncharacterized protein LOC495014)
Gene: rab40c.S

Interactor 2: Q7ZX67 (Q7ZX67)
small monomeric GTPase (EC 3.6.5.2)
Gene: rap2a.S

Species: Xenopus laevis

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.50	1.00	0.713

Property	Details
Experiments	17627283
Identification Methods	two hybrid, pull down
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Ras~Ras
Common GO terms	GO:0005525 - GTP binding GO:0005886 - plasma membrane
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 286 Xl			1 183
+	Hs
		897980 RB40B_HUMAN (1-286): 5.39e-101: 298: 78.32		RAP2B_HUMAN (1-182): 1.49e-82: 243: 90.66
+	Hs
		486023 RB40B_HUMAN (1-286): 5.39e-101: 298: 78.32		RAP2A_HUMAN (1-183): 5.24e-82: 242: 98.91
+	Hs
		1017285 RB40B_HUMAN (1-286): 5.39e-101: 298: 78.32		RAP2C_HUMAN (1-183): 2.35e-81: 240: 90.16
+	Hs
		1273009 RAB8B_HUMAN (7-177): 2.79e-96: 283: 45.93		RAB1B_HUMAN (4-180): 1.38e-76: 229: 33.71
+	Hs
		895217 RAB8B_HUMAN (7-177): 2.79e-96: 283: 45.93		RAB2A_HUMAN (4-183): 1.49e-74: 224: 34.81
+	Zm
		73944 B4FAE1_MAIZE (7-198): 9.75e-89: 264: 36.45		B4FAE1_MAIZE (4-178): 1.46e-79: 236: 36.93
+	Hs
		918846 RAB1A_HUMAN (4-197): 1.74e-87: 261: 37.56		RAB1A_HUMAN (4-183): 6.6e-80: 237: 34.25
+	Dm
		185469 O18332_DROME (4-197): 7.13e-85: 254: 36.59		RAP1_DROME (1-165): 6.95e-81: 239: 64.24
+	Hs
		913992 RAB1A_HUMAN (4-197): 1.74e-87: 261: 37.56		RB11A_HUMAN (4-179): 1.15e-76: 229: 30.51
+	Hs
		918944 RAB1A_HUMAN (4-197): 1.74e-87: 261: 37.56		RAB1B_HUMAN (4-180): 1.38e-76: 229: 33.71
+	Hs
		895216 RAB1C_HUMAN (7-197): 2.23e-89: 265: 37.81		RAB2A_HUMAN (4-183): 1.49e-74: 224: 34.81
+	Mm
		919000 RAB1A_MOUSE (4-197): 1.74e-87: 261: 37.56		RAB1B_MOUSE (4-180): 3.77e-76: 228: 33.71
+	Hs
		895026 RAB1A_HUMAN (4-197): 1.74e-87: 261: 37.56		RAB2A_HUMAN (4-183): 1.49e-74: 224: 34.81
+	Hs
		896605 RAB1A_HUMAN (4-197): 1.74e-87: 261: 37.56		RAB14_HUMAN (4-183): 5.57e-74: 222: 30.39
+	Hs
		895264 RAB1B_HUMAN (7-197): 7.03e-85: 254: 36.82		RAB2A_HUMAN (4-183): 1.49e-74: 224: 34.81
+	Dm
		185461 O18332_DROME (4-197): 7.13e-85: 254: 36.59		RAB2_DROME (4-183): 1.32e-73: 222: 33.70
+	Hs
		896681 RAB1B_HUMAN (7-197): 7.03e-85: 254: 36.82		RAB14_HUMAN (4-183): 5.57e-74: 222: 30.39
+	Hs
		349231 RAB1A_HUMAN (4-197): 1.74e-87: 261: 37.56		RASH_HUMAN (1-180): 2.18e-48: 157: 46.49