HitPredict

Interactor 1: RN123 (Q5XPI4)
E3 ubiquitin-protein ligase RNF123 (EC 2.3.2.27) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123)
Gene: RNF123

Interactor 2: UBE2W (Q96B02)
Ubiquitin-conjugating enzyme E2 W (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme W) (N-terminal E2 ubiquitin-conjugating enzyme) (EC 2.3.2.25) (N-terminus-conjugating E2) (Ubiquitin carrier protein W) (Ubiquitin-conjugating enzyme 16) (UBC-16) (Ubiquitin-protein ligase W)
Gene: UBE2W

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	1.00	0.656

Property	Details
Experiments	19549727
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	UQ_con~zf-C3HC4_3
Common GO terms	GO:0000209 - protein polyubiquitination GO:0004842 - ubiquitin-protein transferase activity GO:0005737 - cytoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1314 Hs			1 151
+	Hs
		849340 RN123_HUMAN (1-1314): 0: 1932: 100.00		UB2D1_HUMAN (4-150): 2.02e-69: 207: 34.69
+	Hs
		919750 RN123_HUMAN (1-1314): 0: 1932: 100.00		UB2D2_HUMAN (4-150): 1.14e-68: 205: 33.33
+	Hs
		829018 RN123_HUMAN (1-1314): 0: 1932: 100.00		UBE2A_HUMAN (1-146): 7.59e-64: 193: 31.97
+	Hs
		829057 HNRL1_HUMAN (21-383): 8.77e-71: 257: 17.69		UBE2A_HUMAN (1-146): 7.59e-64: 193: 31.97
+	Hs
		919818 RSPRY_HUMAN (60-297): 2.82e-61: 222: 27.38		UB2D2_HUMAN (4-150): 1.14e-68: 205: 33.33
+	Hs
		895872 RSPRY_HUMAN (60-297): 2.82e-61: 222: 27.38		UB2D3_HUMAN (4-150): 3.12e-67: 202: 33.33
+	Ce
		72455 B3WFX6_CAEEL (88-294): 4e-47: 181: 27.44		UBC2_CAEEL (4-150): 6.67e-69: 206: 34.01
+	Zm
		35306 A0A1D6Q353_MAIZE (65-273): 5.11e-47: 178: 17.20		A0A1D6LKH6_MAIZE (1-148): 1.2e-63: 194: 30.20