HitPredict

Interactor 1: Q5ZEW1 (Q5ZEW1)
receptor protein-tyrosine kinase (EC 2.7.10.1)
Gene: epha4a

Interactor 2: Q90YC5 (Q90YC5)
Ephrin-A3 (Ephrin-A3b)
Gene: efna3b

Species: Danio rerio

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	26190107
Identification Methods	avexis
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ephrin~Ephrin_lbd
Common GO terms	GO:0005886 - plasma membrane GO:0007411 - axon guidance
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 986 Dr			1 219
+	Dr
		47532 Q5ZEW1_DANRE (1-986): 0: 1270: 100.00		A0A8M1Q1X6_DANRE (1-206): 4.05e-87: 258: 75.94
+	Dr
		945416 Q5ZEW1_DANRE (1-986): 0: 1270: 100.00		EFNA5_DANRE (6-203): 1.88e-67: 208: 41.29
+	Dr
		945415 Q5ZEW1_DANRE (1-986): 0: 1270: 100.00		EFNA2_DANRE (6-171): 6.25e-66: 203: 46.82
+	Dr
		251124 Q5ZEW1_DANRE (1-986): 0: 1270: 100.00		EFNB2_DANRE (2-196): 1e-62: 199: 23.53
+	Dr
		1140993 Q5ZEW1_DANRE (1-986): 0: 1270: 100.00		Q90Z31_DANRE (10-200): 2.58e-61: 196: 22.44
+	Hs
		595985 EPHA4_HUMAN (1-986): 0: 1220: 82.27		EFNA1_HUMAN (10-190): 1.13e-76: 231: 43.48
+	Hs
		856319 EPHA7_HUMAN (6-986): 0: 1174: 61.71		EFNA3_HUMAN (18-209): 3.27e-88: 261: 65.03
+	Hs
		856510 EPHA4_HUMAN (1-986): 0: 1220: 82.27		EFNB2_HUMAN (2-176): 8.76e-69: 215: 26.09
+	Hs
		856597 EPHA4_HUMAN (1-986): 0: 1220: 82.27		EFNA5_HUMAN (1-187): 2.62e-70: 215: 40.53
+	Mm
		856591 EPHA4_MOUSE (1-986): 0: 1214: 82.17		EFNB2_MOUSE (2-176): 1.92e-67: 212: 26.09
+	Dr
		47531 A0A8M9PHF0_DANRE (10-986): 0: 1157: 61.24		A0A8M1Q1X6_DANRE (1-206): 4.05e-87: 258: 75.94
+	Hs
		856348 EPHA4_HUMAN (1-986): 0: 1220: 82.27		EFNA4_HUMAN (1-161): 1.12e-61: 193: 37.81
+	Hs
		217636 EPHA4_HUMAN (1-986): 0: 1220: 82.27		EFNA2_HUMAN (18-166): 1.02e-57: 183: 49.69
+	Mm
		139053 EPHA7_MOUSE (1-986): 0: 1173: 61.40		EFNA5_MOUSE (1-187): 2.02e-70: 216: 41.05
+	Hs
		856606 EPHA7_HUMAN (6-986): 0: 1174: 61.71		EFNA5_HUMAN (1-187): 2.62e-70: 215: 40.53
+	Hs
		872654 EPHA4_HUMAN (1-986): 0: 1220: 82.27		EFNB3_HUMAN (26-201): 1.63e-49: 166: 25.00
+	Hs
		957840 EPHA7_HUMAN (6-986): 0: 1174: 61.71		EFNB1_HUMAN (3-179): 1.37e-62: 199: 24.73
+	Hs
		856385 EPHA7_HUMAN (6-986): 0: 1174: 61.71		EFNA4_HUMAN (1-161): 1.12e-61: 193: 37.81
+	Hs
		217642 EPHA7_HUMAN (6-986): 0: 1174: 61.71		EFNA2_HUMAN (18-166): 1.02e-57: 183: 49.69
+	Dr
		47564 A0A8M9PHF0_DANRE (10-986): 0: 1157: 61.24		EFNB2_DANRE (2-196): 1e-62: 199: 23.53