Interactor 1: DYR (Q60034)
Dihydrofolate reductase (DHFR) (EC 1.5.1.3)
Gene: folA

Interactor 2: DYR (Q60034)
Dihydrofolate reductase (DHFR) (EC 1.5.1.3)
Gene: folA

Species: Thermotoga maritima MSB8

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 10731419
Identification Methods x-ray crystallography
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains DHFR_1~DHFR_1
Common GO terms GO:0004146 - dihydrofolate reductase activity
GO:0005829 - cytosol
GO:0006545 - glycine biosynthetic process
GO:0006730 - one-carbon metabolic process
GO:0046452 - dihydrofolate metabolic process
and 3 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 169
Tm

1 169
+ Ca
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024