HitPredict

Interactor 1: SIN3A (Q60520)
Paired amphipathic helix protein Sin3a (Histone deacetylase complex subunit Sin3a) (Transcriptional corepressor Sin3a)
Gene: SIN3A

Interactor 2: MECP2 (Q9Z2D6)
Methyl-CpG-binding protein 2 (MeCp-2 protein) (MeCp2)
Gene: MECP2

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.71 0.60 0.656

The method score is based on:

Property Details
Experiments 22119903, 23770565, 19602036
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0003677 - DNA binding
GO:0003682 - chromatin binding
GO:0003714 - transcription corepressor activity
and 6 others

more...
Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 1274
Mm

1 484
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024