HitPredict

Interactor 1: ITF2 (Q60722)
Transcription factor 4 (TCF-4) (Class A helix-loop-helix transcription factor ME2) (Immunoglobulin transcription factor 2) (ITF-2) (MITF-2) (SL3-3 enhancer factor 2) (SEF-2)
Gene: Tcf4

Interactor 2: Q6GTZ3 (Q6GTZ3)
Idb1 protein (Inhibitor of DNA binding 1)
Gene: Id1

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	1.00	0.698

Property	Details
Experiments	20211142
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	HLH~HLH
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0030154 - cell differentiation
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 670 Mm			1 148
+	Hs
		551084 ITF2_HUMAN (1-670): 0: 891: 97.32		ID1_HUMAN (14-148): 2.34e-70: 210: 90.78
+	Mm
		781006 ITF2_MOUSE (1-670): 0: 927: 100.00		ID2_MOUSE (17-147): 8.34e-45: 144: 42.14
+	Mm
		780944 ITF2_MOUSE (1-670): 0: 927: 100.00		ID3_MOUSE (17-121): 2.45e-42: 138: 44.76
+	Hs
		551118 ITF2_HUMAN (1-670): 0: 891: 97.32		ID2_HUMAN (17-147): 8.93e-44: 142: 42.86
+	Hs
		551119 ITF2_HUMAN (1-670): 0: 891: 97.32		ID3_HUMAN (17-121): 2.32e-42: 138: 45.71
+	Hs
		551089 ITF2_HUMAN (1-670): 0: 891: 97.32		ID4_HUMAN (61-148): 7.55e-34: 117: 46.00
+	Mm
		1142448 HTF4_MOUSE (3-670): 0: 778: 59.72		Q6GTZ3_MOUSE (1-148): 1.8e-76: 225: 100.00
+	Hs
		780982 HTF4_HUMAN (3-670): 0: 787: 62.52		ID1_HUMAN (14-148): 2.34e-70: 210: 90.78
+	Hs
		551478 TFE2_HUMAN (1-670): 0: 721: 50.36		ID1_HUMAN (14-148): 2.34e-70: 210: 90.78
+	Hs
		970599 HTF4_HUMAN (3-670): 0: 787: 62.52		ID2_HUMAN (17-147): 8.93e-44: 142: 42.86
+	Hs
		971137 HTF4_HUMAN (3-670): 0: 787: 62.52		ID3_HUMAN (17-121): 2.32e-42: 138: 45.71
+	Mm
		781007 HTF4_MOUSE (3-670): 0: 778: 59.72		ID2_MOUSE (17-147): 8.34e-45: 144: 42.14
+	Mm
		780945 HTF4_MOUSE (3-670): 0: 778: 59.72		ID3_MOUSE (17-121): 2.45e-42: 138: 44.76
+	Hs
		814913 HTF4_HUMAN (3-670): 0: 787: 62.52		ID4_HUMAN (61-148): 7.55e-34: 117: 46.00
+	Mm
		589142 Q91XK1_MOUSE (182-670): 0: 688: 99.80		ID1_MOUSE (1-135): 6.25e-70: 209: 100.00
+	Hs
		551502 TFE2_HUMAN (1-670): 0: 721: 50.36		ID2_HUMAN (17-147): 8.93e-44: 142: 42.86
+	Hs
		551503 TFE2_HUMAN (1-670): 0: 721: 50.36		ID3_HUMAN (17-121): 2.32e-42: 138: 45.71
+	Rn
		600264 TFE2_RAT (1-670): 0: 703: 48.28		ID3_RAT (17-121): 1.17e-42: 139: 45.71
+	Hs
		551480 TFE2_HUMAN (1-670): 0: 721: 50.36		ID4_HUMAN (61-148): 7.55e-34: 117: 46.00
+	Mm
		780947 Q91XK1_MOUSE (182-670): 0: 688: 99.80		ID3_MOUSE (17-121): 2.45e-42: 138: 44.76