HitPredict

Interactor 1: DVL2 (Q60838)
Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2)
Gene: DVL2

Interactor 2: TAOK2 (Q6ZQ29)
Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Thousand and one amino acid protein 2)
Gene: TAOK2

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36417873
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005856 - cytoskeleton GO:0046330 - positive regulation of JNK cascade
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 736 Mm			1 1240
+	Mm
		844425 DVL1_MOUSE (11-736): 7.31e-159: 478: 58.27		TAOK2_MOUSE (1-1240): 0: 1235: 100.00
+	Mm
		1142088 DVL3_MOUSE (11-736): 5.25e-153: 463: 64.63		TAOK2_MOUSE (1-1240): 0: 1235: 100.00
+	Mm
		1169681 AFAD_MOUSE (261-681): 1.04e-71: 257: 19.04		TAOK2_MOUSE (1-1240): 0: 1235: 100.00
+	Mm
		936182 DLG3_MOUSE (75-536): 7.34e-45: 175: 17.01		TAOK2_MOUSE (1-1240): 0: 1235: 100.00
+	Hs
		150862 DVL2_HUMAN (1-736): 3.28e-180: 534: 96.60		MARK3_HUMAN (2-700): 1.3e-152: 478: 15.37
+	Hs
		151058 DVL2_HUMAN (1-736): 3.28e-180: 534: 96.60		MARK2_HUMAN (5-700): 1.36e-142: 453: 15.20
+	Hs
		151228 DVL2_HUMAN (1-736): 3.28e-180: 534: 96.60		MARK1_HUMAN (2-700): 5.38e-133: 428: 15.83
+	Hs
		647919 RIMS1_HUMAN (85-722): 4.93e-50: 192: 13.83		MARK3_HUMAN (2-700): 1.3e-152: 478: 15.37
+	Mm
		103564 DVL1_MOUSE (11-736): 7.31e-159: 478: 58.27		G5E884_MOUSE (23-302): 1.8e-50: 189: 40.91
+	Hs
		647852 AFAD_HUMAN (261-701): 1.31e-43: 172: 19.40		MARK3_HUMAN (2-700): 1.3e-152: 478: 15.37
+	Hs
		876374 AFAD_HUMAN (261-701): 1.31e-43: 172: 19.40		ROCK1_HUMAN (25-889): 5.36e-145: 475: 17.01
+	Hs
		1183080 PAR3L_HUMAN (205-668): 1.46e-50: 193: 16.91		MARK2_HUMAN (5-700): 1.36e-142: 453: 15.20
+	Hs
		1183065 RIMS1_HUMAN (85-722): 4.93e-50: 192: 13.83		MARK2_HUMAN (5-700): 1.36e-142: 453: 15.20
+	Hs
		1200039 RIMS1_HUMAN (85-722): 4.93e-50: 192: 13.83		MRCKB_HUMAN (9-949): 2.27e-128: 435: 15.42
+	Hs
		876427 AFAD_HUMAN (261-701): 1.31e-43: 172: 19.40		MARK2_HUMAN (5-700): 1.36e-142: 453: 15.20
+	Hs
		1200015 RIMS1_HUMAN (85-722): 4.93e-50: 192: 13.83		MARK1_HUMAN (2-700): 5.38e-133: 428: 15.83
+	Mm
		949354 DLG1_MOUSE (95-708): 1.25e-48: 186: 15.46		TNIK_MOUSE (1-305): 3.16e-50: 197: 40.49
+	Mm
		936174 DLG3_MOUSE (75-536): 7.34e-45: 175: 17.01		TNIK_MOUSE (1-305): 3.16e-50: 197: 40.49
+	Mm
		949403 RIMS1_MOUSE (61-696): 2.15e-43: 171: 13.62		TNIK_MOUSE (1-305): 3.16e-50: 197: 40.49
+	Mm
		949394 DLG2_MOUSE (135-640): 1.18e-24: 112: 13.65		TNIK_MOUSE (1-305): 3.16e-50: 197: 40.49