HitPredict

Interactor 1: RIPK1 (Q60855)
Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Cell death protein RIP) (Receptor-interacting protein 1) (RIP-1)
Gene: RIPK1

Interactor 2: ITCH (Q8C863)
E3 ubiquitin-protein ligase Itchy (EC 2.3.2.26) (HECT-type E3 ubiquitin transferase Itchy homolog)
Gene: ITCH

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.60 0.60 0.601

The method score is based on:

Property Details
Experiments 18246070, 21765415
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0006915 - apoptotic process
GO:0030163 - protein catabolic process
GO:0043066 - negative regulation of apoptotic process
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 656
Mm

1 864
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024