Interactor 1: RIPK1 (Q60855)
Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Cell death protein RIP) (Receptor-interacting protein 1) (RIP-1)
Gene: RIPK1

Interactor 2: ZBP1 (Q9QY24)
Z-DNA-binding protein 1 (DNA-dependent activator of IFN-regulatory factors) (DAI) (Tumor stroma and activated macrophage protein DLM-1)
Gene: ZBP1

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 19590578
Identification Methods anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains RHIM~RHIM
Common GO terms GO:0006915 - apoptotic process
GO:0043065 - positive regulation of apoptotic process
GO:0050729 - positive regulation of inflammatory response
GO:0060545 - positive regulation of necroptotic process
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 656
Mm

1 411
+ Hs
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024