HitPredict

Interactor 1: SC6A4 (Q60857)
Sodium-dependent serotonin transporter (SERT) (5HT transporter) (5HTT) (Solute carrier family 6 member 4)
Gene: Slc6a4

Interactor 2: NEB2 (Q6R891)
Neurabin-2 (Neurabin-II) (Protein phosphatase 1 regulatory subunit 9B) (Spinophilin)
Gene: Ppp1r9b

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	32581705
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0051015 - actin filament binding
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 630 Mm			1 817
+	Mm
		1141691 SC6A4_MOUSE (1-630): 0: 814: 100.00		DLG2_MOUSE (85-704): 1.1e-42: 169: 13.14
+	Mm
		1141617 SC6A4_MOUSE (1-630): 0: 814: 100.00		DLG1_MOUSE (244-705): 2.57e-41: 165: 15.98
+	Mm
		1141601 SC6A4_MOUSE (1-630): 0: 814: 100.00		ERBIN_MOUSE (40-585): 1.14e-39: 160: 13.73
+	Mm
		936179 SC6A4_MOUSE (1-630): 0: 814: 100.00		DLG3_MOUSE (224-734): 1.59e-39: 159: 16.23
+	Mm
		1141556 SC6A4_MOUSE (1-630): 0: 814: 100.00		DLG4_MOUSE (381-806): 1.83e-31: 133: 11.04
+	Mm
		1141743 SC6A4_MOUSE (1-630): 0: 814: 100.00		MAGI3_MOUSE (130-689): 1.75e-19: 96.2: 11.75
+	Mm
		1141564 SC6A4_MOUSE (1-630): 0: 814: 100.00		PTN13_MOUSE (51-810): 3.5e-18: 92.4: 11.40
+	Mm
		1141587 SC6A4_MOUSE (1-630): 0: 814: 100.00		MAGI1_MOUSE (402-794): 6.08e-16: 84.7: 12.28
+	Mm
		1141563 SC6A4_MOUSE (1-630): 0: 814: 100.00		INADL_MOUSE (475-595): 1.73e-11: 70.4: 21.95
+	Hs
		1252563 SC6A5_HUMAN (50-617): 0: 678: 40.50		LNX1_HUMAN (224-773): 4.36e-33: 138: 11.92
+	Mm
		681265 SC6A1_MOUSE (33-621): 0: 650: 41.02		LNX2_MOUSE (13-580): 4.46e-37: 150: 11.00
+	Mm
		250599 SC6A1_MOUSE (33-621): 0: 650: 41.02		LNX1_MOUSE (224-773): 2.22e-30: 130: 12.21
+	Hs
		815756 SC6A8_HUMAN (23-614): 0: 621: 40.92		AFAD_HUMAN (397-798): 1.76e-38: 157: 18.69
+	Mm
		1142533 SC6A3_MOUSE (35-620): 0: 699: 47.97		INADL_MOUSE (475-595): 1.73e-11: 70.4: 21.95
+	Mm
		192599 SC6A6_MOUSE (59-617): 0: 626: 43.31		DLG4_MOUSE (381-806): 1.83e-31: 133: 11.04
+	Rn
		659340 SC6A9_RAT (49-617): 0: 624: 40.48		DLG4_RAT (438-714): 2.14e-29: 127: 16.03
+	Hs
		876502 S6A15_HUMAN (67-596): 0: 558: 30.91		AFAD_HUMAN (397-798): 1.76e-38: 157: 18.69
+	Hs
		1252473 S6A15_HUMAN (67-596): 0: 558: 30.91		LNX1_HUMAN (224-773): 4.36e-33: 138: 11.92
+	Ce
		101935 SNF6_CAEEL (73-615): 8.66e-177: 520: 30.88		G1K0W3_CAEEL (463-768): 9.4e-21: 100: 12.77