HitPredict

Interactor 1: RBBP4 (Q60972)
Histone-binding protein RBBP4 (Chromatin assembly factor 1 subunit C) (CAF-1 subunit C) (Chromatin assembly factor I p48 subunit) (CAF-I 48 kDa subunit) (CAF-I p48) (Nucleosome-remodeling factor subunit RBAP48) (Retinoblastoma-binding protein 4) (RBBP-4) (Retinoblastoma-binding protein p48)
Gene: RBBP4

Interactor 2: EHMT2 (Q9Z148)
Histone-lysine N-methyltransferase EHMT2 (EC 2.1.1.-) (EC 2.1.1.367) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Protein G9a)
Gene: EHMT2

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	25680957
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	SET~WD40
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 425 Mm			1 1263
+	Hs
		903444 WDR5_HUMAN (267-425): 7.48e-35: 133: 25.61		EHMT2_HUMAN (78-1263): 0: 867: 94.97
+	Hs
		203672 RBBP4_HUMAN (1-425): 4.3e-124: 367: 100.00		SUV91_HUMAN (914-1230): 8.33e-88: 293: 31.53
+	Mm
		222465 RBBP4_MOUSE (1-425): 4.3e-124: 367: 100.00		SUV91_MOUSE (987-1230): 7.05e-85: 285: 35.40
+	Hs
		203695 RBBP7_HUMAN (1-425): 3.63e-115: 345: 89.20		SUV91_HUMAN (914-1230): 8.33e-88: 293: 31.53
+	Mm
		222466 RBBP7_MOUSE (1-425): 1.21e-114: 343: 89.20		SUV91_MOUSE (987-1230): 7.05e-85: 285: 35.40
+	Hs
		203735 DAW1_HUMAN (9-106): 2.42e-20: 94.1: 8.74		SUV91_HUMAN (914-1230): 8.33e-88: 293: 31.53
+	Hs
		903354 WDR5_HUMAN (267-425): 7.48e-35: 133: 25.61		ANKH1_HUMAN (79-823): 3.59e-46: 184: 12.95