HitPredict

Interactor 1: Q60I23 (Q60I23)
SRY (sex determining region Y)-box 2 (Sox2 protein) (Transcriptional factor SOX2)
Gene: Sox2

Interactor 2: TBL1R (Q8BHJ5)
F-box-like/WD repeat-containing protein TBL1XR1 (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1) (TBL1-related protein 1) (Transducin beta-like 1X-related protein 1)
Gene: Tbl1xr1

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.39	0.60	0.484

Property	Details
Experiments	21532573
Identification Methods	anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 319 Mm			1 514
+	Hs
		818441 SOX2_HUMAN (1-319): 1.7e-62: 202: 96.24		TBL1R_HUMAN (1-514): 1.85e-158: 462: 99.03
+	Hs
		245575 SOX2_HUMAN (1-319): 1.7e-62: 202: 96.24		TBL1X_HUMAN (1-514): 3.65e-145: 430: 85.96
+	Hs
		996881 SSRP1_HUMAN (21-210): 1.09e-30: 124: 15.71		TBL1R_HUMAN (1-514): 1.85e-158: 462: 99.03
+	Hs
		245569 SOX5_HUMAN (17-129): 1.06e-39: 150: 40.71		TBL1X_HUMAN (1-514): 3.65e-145: 430: 85.96
+	Hs
		245570 SOX6_HUMAN (18-202): 1.01e-33: 132: 29.73		TBL1X_HUMAN (1-514): 3.65e-145: 430: 85.96
+	Hs
		245594 SSRP1_HUMAN (21-210): 1.09e-30: 124: 15.71		TBL1X_HUMAN (1-514): 3.65e-145: 430: 85.96
+	Hs
		245636 SOX17_HUMAN (17-285): 5.22e-31: 122: 26.02		TBL1X_HUMAN (1-514): 3.65e-145: 430: 85.96
+	Hs
		817868 SOX2_HUMAN (1-319): 1.7e-62: 202: 96.24		WDR5_HUMAN (16-293): 1.56e-42: 156: 13.59
+	Hs
		996930 SSRP1_HUMAN (21-210): 1.09e-30: 124: 15.71		NLE1_HUMAN (13-293): 8.97e-48: 174: 14.69
+	Hs
		903450 CIC_HUMAN (10-274): 1.46e-36: 141: 24.28		WDR5_HUMAN (16-293): 1.56e-42: 156: 13.59
+	Hs
		817979 SOX2_HUMAN (1-319): 1.7e-62: 202: 96.24		TBL3_HUMAN (9-197): 2.3e-18: 90.6: 10.53
+	Hs
		996921 SSRP1_HUMAN (21-210): 1.09e-30: 124: 15.71		BRWD1_HUMAN (299-514): 9.06e-44: 168: 18.42
+	Hs
		1103013 CIC_HUMAN (10-274): 1.46e-36: 141: 24.28		SMU1_HUMAN (329-513): 8.45e-39: 150: 19.00
+	Hs
		996721 SSRP1_HUMAN (21-210): 1.09e-30: 124: 15.71		BRWD3_HUMAN (302-514): 1.46e-43: 167: 19.30
+	Hs
		903169 SSRP1_HUMAN (21-210): 1.09e-30: 124: 15.71		WDR5_HUMAN (16-293): 1.56e-42: 156: 13.59
+	Hs
		996824 SSRP1_HUMAN (21-210): 1.09e-30: 124: 15.71		SNR40_HUMAN (341-514): 2.25e-41: 153: 27.84
+	Hs
		818834 SOX9_HUMAN (27-262): 3.13e-35: 135: 27.24		FBXW7_HUMAN (160-330): 1.87e-25: 112: 23.20
+	Hs
		996813 SSRP1_HUMAN (21-210): 1.09e-30: 124: 15.71		FBXW7_HUMAN (160-330): 1.87e-25: 112: 23.20
+	Hs
		133757 SOX1_HUMAN (4-319): 4.34e-33: 127: 46.55		CIAO1_HUMAN (169-472): 3.77e-22: 99.4: 27.94
+	Hs
		1074805 CIC_HUMAN (10-274): 1.46e-36: 141: 24.28		TAF5_HUMAN (164-376): 5.96e-14: 76.6: 23.72