HitPredict

Interactor 1: KSR1 (Q61097)
Kinase suppressor of Ras 1 (mKSR1) (EC 2.7.11.1) (Protein Hb)
Gene: KSR1

Interactor 2: MP2K2 (Q63932)
Dual specificity mitogen-activated protein kinase kinase 2 (MAP kinase kinase 2) (MAPKK 2) (EC 2.7.12.2) (ERK activator kinase 2) (MAPK/ERK kinase 2) (MEK 2)
Gene: Map2k2

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.76 1.00 0.873

The method score is based on:

Property Details
Experiments 21144847, 12932319, 17174095, 15121859
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PK_Tyr_Ser-Thr~Pkinase
Common GO terms GO:0004674 - protein serine/threonine kinase activity
GO:0005078 - MAP-kinase scaffold activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005783 - endoplasmic reticulum
and 4 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 873
Mm

1 401
+ Mm
+ Rn
+ Rn
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Gg
+ Hs
+ Gg
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024