HitPredict

Interactor 1: TRPC6 (Q61143)
Short transient receptor potential channel 6 (TrpC6) (Calcium entry channel) (Transient receptor protein 6) (TRP-6)
Gene: TRPC6

Interactor 2: PODO (Q91X05)
Podocin
Gene: Nphs2

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	23657570, 17079490
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0036057 - slit diaphragm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 930 Mm			1 385
+	Mm
		1265152 TRPC3_MOUSE (101-922): 0: 617: 71.24		PODO_MOUSE (1-385): 7.64e-143: 412: 100.00
+	Mm
		1265150 TRPC5_MOUSE (98-913): 1.3e-163: 505: 35.81		PODO_MOUSE (1-385): 7.64e-143: 412: 100.00
+	Mm
		1265149 TRPC4_MOUSE (98-929): 1.12e-157: 490: 36.72		PODO_MOUSE (1-385): 7.64e-143: 412: 100.00
+	Mm
		1265156 TRPC2_MOUSE (101-916): 3.99e-145: 462: 33.96		PODO_MOUSE (1-385): 7.64e-143: 412: 100.00
+	Mm
		1142085 TRPC1_MOUSE (84-909): 4.12e-141: 441: 33.73		PODO_MOUSE (1-385): 7.64e-143: 412: 100.00
+	Hs
		719207 TRPC4_HUMAN (98-929): 9.01e-159: 493: 36.78		PHB1_HUMAN (111-355): 1.49e-65: 211: 15.15
+	Mm
		192465 PKD2_MOUSE (431-840): 1.91e-50: 194: 16.55		PODO_MOUSE (1-385): 7.64e-143: 412: 100.00