Interactor 1: FADD (Q61160)
FAS-associated death domain protein (FAS-associating death domain-containing protein) (Mediator of receptor induced toxicity)
Gene: FADD

Interactor 2: MLKL (Q9D2Y4)
Mixed lineage kinase domain-like protein
Gene: MLKL

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 29203883
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0044877 - protein-containing complex binding
GO:0051607 - defense response to virus
GO:0097527 - necroptotic signaling pathway
Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 205
Mm

1 472
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024