HitPredict

Interactor 1: FADD (Q61160)
FAS-associated death domain protein (FAS-associating death domain-containing protein) (Mediator of receptor induced toxicity)
Gene: FADD

Interactor 2: RIPK3 (Q9QZL0)
Receptor-interacting serine/threonine-protein kinase 3 (EC 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) (mRIP3)
Gene: RIPK3

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.86 1.00 0.931

The method score is based on:

Property Details
Experiments 30420664, 26649818, 24557836, 21368763, 19524513, 21052097
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains DED~Pkinase
Common GO terms GO:0006915 - apoptotic process
GO:0032991 - protein-containing complex
GO:0033077 - T cell differentiation in thymus
GO:0043029 - T cell homeostasis
GO:0044877 - protein-containing complex binding
and 5 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 205
Mm

1 486
+ Hs
+ Hs
+ Mm
+ Hs
+ Mm
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024