HitPredict

Interactor 1: M9PBM3 (M9PBM3)
Cysteine protease (EC 3.4.22.-)
Gene: Atg4a

Interactor 2: Q9VEG5 (Q9VEG5)
Autophagy-related 8b, isoform A (Autophagy-related 8b, isoform B) (GEO01803p1)
Gene: Atg8b

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	14605208
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	ATG8~Peptidase_C54
Common GO terms	GO:0000045 - autophagosome assembly GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 410 Dm			1 120
+	Dm
		1179054 Q9VPW2_DROME (1-410): 0: 643: 99.76		Q7K1J3_DROME (1-120): 5.66e-57: 175: 100.00
+	Dm
		1372164 Q9VPW2_DROME (1-410): 0: 643: 99.76		Q9W2S2_DROME (3-118): 9.86e-58: 175: 82.76
+	Dm
		1364631 Q9VPW2_DROME (1-410): 0: 643: 99.76		Q9VEG5_DROME (1-120): 5.34e-57: 174: 100.00
+	Hs
		891370 ATG4B_HUMAN (38-354): 5.93e-165: 470: 44.13		GBRL2_HUMAN (3-118): 9.58e-58: 175: 51.72
+	Hs
		306368 ATG4B_HUMAN (38-354): 5.93e-165: 470: 44.13		GBRAP_HUMAN (3-118): 1.47e-56: 172: 77.59
+	Hs
		1328075 ATG4B_HUMAN (38-354): 5.93e-165: 470: 44.13		GBRL1_HUMAN (3-119): 4.03e-56: 171: 73.50
+	Hs
		891248 ATG4A_HUMAN (13-355): 2.79e-158: 453: 40.75		GBRL2_HUMAN (3-118): 9.58e-58: 175: 51.72
+	Hs
		306253 ATG4A_HUMAN (13-355): 2.79e-158: 453: 40.75		GBRAP_HUMAN (3-118): 1.47e-56: 172: 77.59
+	Hs
		1264549 ATG4A_HUMAN (13-355): 2.79e-158: 453: 40.75		GBRL1_HUMAN (3-119): 4.03e-56: 171: 73.50
+	Mm
		1206409 ATG4B_MOUSE (38-354): 3.39e-166: 473: 43.55		MLP3A_MOUSE (1-118): 2.88e-47: 149: 31.67
+	Hs
		1330686 ATG4B_HUMAN (38-354): 5.93e-165: 470: 44.13		MLP3A_HUMAN (1-118): 2.88e-47: 149: 31.67
+	Hs
		1315816 ATG4B_HUMAN (38-354): 5.93e-165: 470: 44.13		MLP3C_HUMAN (1-118): 5.2e-46: 147: 36.67
+	Hs
		1326231 ATG4B_HUMAN (38-354): 5.93e-165: 470: 44.13		MLP3B_HUMAN (1-118): 1.86e-45: 145: 29.17
+	Hs
		61909 ATG4B_HUMAN (38-354): 5.93e-165: 470: 44.13		MP3B2_HUMAN (1-118): 1.15e-44: 143: 28.33
+	Hs
		1264550 ATG4A_HUMAN (13-355): 2.79e-158: 453: 40.75		MLP3A_HUMAN (1-118): 2.88e-47: 149: 31.67
+	Hs
		1264548 ATG4A_HUMAN (13-355): 2.79e-158: 453: 40.75		MLP3B_HUMAN (1-118): 1.86e-45: 145: 29.17
+	Hs
		891203 ATG4D_HUMAN (48-366): 4.6e-143: 417: 32.97		GBRL2_HUMAN (3-118): 9.58e-58: 175: 51.72
+	Hs
		306219 ATG4D_HUMAN (48-366): 4.6e-143: 417: 32.97		GBRAP_HUMAN (3-118): 1.47e-56: 172: 77.59
+	Hs
		1198603 ATG4D_HUMAN (48-366): 4.6e-143: 417: 32.97		GBRL1_HUMAN (3-119): 4.03e-56: 171: 73.50
+	Hs
		1198602 ATG4D_HUMAN (48-366): 4.6e-143: 417: 32.97		MLP3B_HUMAN (1-118): 1.86e-45: 145: 29.17