Interactor 1: EZH2 (Q61188)
Histone-lysine N-methyltransferase EZH2 (EC 2.1.1.356) (ENX-1) (Enhancer of zeste homolog 2)
Gene: EZH2

Interactor 2: EZH2 (Q61188)
Histone-lysine N-methyltransferase EZH2 (EC 2.1.1.356) (ENX-1) (Enhancer of zeste homolog 2)
Gene: EZH2

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 25680957
Identification Methods proximity labelling technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PRC2_HTH_1~PRC2_HTH_1, SET~preSET_CXC, SET~SET
Common GO terms GO:0000082 - G1/S transition of mitotic cell cycle
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000781 - chromosome, telomeric region
GO:0000976 - transcription cis-regulatory region binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
and 75 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 746
Mm

1 746
+ Hs
+ Mm
+ Hs
+ Mm
+ Hs
+ Dm
+ Hs
+ Hs
+ Hs
+ Mm
+ Mm
+ Hs
+ Mm
+ Mm
+ Hs
+ Zm
+ At
+ Dm

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Last updated: 15 Jul 2024