Interactor 1: EZH2 (Q61188)
Histone-lysine N-methyltransferase EZH2 (EC 2.1.1.356) (ENX-1) (Enhancer of zeste homolog 2)
Gene: EZH2

Interactor 2: JARD2 (Q62315)
Protein Jumonji (Jumonji/ARID domain-containing protein 2)
Gene: Jarid2

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.89 0.60 0.732

The method score is based on:

Property Details
Experiments 25680957, 20123894, 20064375, 20064376, 20075857, 21811233
Identification Methods proximity labelling technology, affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, molecular sieving
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0003677 - DNA binding
GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0010468 - regulation of gene expression
and 5 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 746
Mm

1 1234
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+ Sp
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+ Dm

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Last updated: 15 Jul 2024