Interactor 1: EZH2 (Q61188)
Histone-lysine N-methyltransferase EZH2 (EC 2.1.1.356) (ENX-1) (Enhancer of zeste homolog 2)
Gene: EZH2
Interactor 2: EHMT2 (Q9Z148)
Histone-lysine N-methyltransferase EHMT2 (EC 2.1.1.-) (EC 2.1.1.367) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Protein G9a)
Gene: EHMT2
Species: Mus musculus
Source: biogrid
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.44 | 1.00 | 0.665 |
The method score is based on:
Property | Details |
---|---|
Experiments | 25680957 |
Identification Methods | proximity labelling technology, affinity chromatography technology |
Interaction Type | physical association |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | SET~preSET_CXC, Ank~SET, Pre-SET~SET |
Common GO terms | GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0001222 - transcription corepressor binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006346 - DNA methylation-dependent heterochromatin formation and 4 others more... |
Homologous interactions | 17 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024