HitPredict - High confidence protein-protein interactions

Interactor 1: MRE11 (Q61216)
Double-strand break repair protein MRE11 (EC 3.1.-.-) (Meiotic recombination 11 homolog 1) (MRE11 homolog 1) (Meiotic recombination 11 homolog A) (MRE11 homolog A) (MmMRE11A)
Gene: MRE11

Interactor 2: NBN (Q9R207)
Nibrin (Cell cycle regulatory protein p95) (Nijmegen breakage syndrome protein 1 homolog)
Gene: NBN

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.633

Property	Details
Experiments	21884979, 17429352, 18854157
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000723 - telomere maintenance GO:0000724 - double-strand break repair via homologous recombination GO:0000729 - DNA double-strand break processing GO:0000781 - chromosome, telomeric region GO:0005634 - nucleus and 16 others more... GO:0005657 - replication fork GO:0006302 - double-strand break repair GO:0007095 - mitotic G2 DNA damage checkpoint signaling GO:0016605 - PML body GO:0030870 - Mre11 complex GO:0031860 - telomeric 3' overhang formation GO:0031954 - positive regulation of protein autophosphorylation GO:0032206 - positive regulation of telomere maintenance GO:0035825 - homologous recombination GO:0035861 - site of double-strand break GO:0044818 - mitotic G2/M transition checkpoint GO:0046597 - negative regulation of viral entry into host cell GO:0062176 - R-loop processing GO:0070533 - BRCA1-C complex GO:0098687 - chromosomal region GO:0110025 - DNA strand resection involved in replication fork processing
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1	706
Mm

1	751

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024