Interactor 1: HIF1A (Q61221)
Hypoxia-inducible factor 1-alpha (HIF-1-alpha) (HIF1-alpha) (ARNT-interacting protein)
Gene: HIF1A

Interactor 2: EGLN1 (Q91YE3)
Egl nine homolog 1 (EC 1.14.11.29) (Hypoxia-inducible factor prolyl hydroxylase 2) (HIF-PH2) (HIF-prolyl hydroxylase 2) (HPH-2) (Prolyl hydroxylase domain-containing protein 2) (PHD2) (SM-20)
Gene: EGLN1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 23649506
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains 2OG-FeII_Oxy_3~HIF-1
Common GO terms GO:0001666 - response to hypoxia
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0006879 - intracellular iron ion homeostasis
GO:0032364 - intracellular oxygen homeostasis
and 3 others

more...

Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 836
Mm

1 400
+ Hs
+ Hs
+ Mm
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024