Interactor 1: ACVL1 (Q61288)
Serine/threonine-protein kinase receptor R3 (SKR3) (EC 2.7.11.30) (Activin receptor-like kinase 1) (ALK-1) (TGF-B superfamily receptor type I) (TSR-I)
Gene: Acvrl1

Interactor 2: EGLN (Q63961)
Endoglin (Cell surface MJ7/18 antigen) (CD antigen CD105)
Gene: Eng

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 0.60 0.584

The method score is based on:

Property Details
Experiments 24319055, 18337748
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001525 - angiogenesis
GO:0003203 - endocardial cushion morphogenesis
GO:0005024 - transforming growth factor beta receptor activity
GO:0007179 - transforming growth factor beta receptor signaling pathway
GO:0007507 - heart development
and 8 others

more...

Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 502
Mm

1 653
+ Hs
+ Mm
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+ Hs
+ Hs
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+ Mm

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Last updated: 15 Jul 2024