Interactor 1: BAD (Q61337)
Bcl2-associated agonist of cell death (BAD) (Bcl-2-binding component 6) (Bcl-xL/Bcl-2-associated death promoter) (Bcl2 antagonist of cell death)
Gene: BAD

Interactor 2: B2CL1 (Q64373)
Bcl-2-like protein 1 (Bcl2-L-1) (Apoptosis regulator Bcl-X)
Gene: Bcl2l1

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.754

The method score is based on:

Property Details
Experiments 21084607, 23332762
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Bcl-2~Bcl-2_BAD
Common GO terms GO:0001836 - release of cytochrome c from mitochondria
GO:0005739 - mitochondrion
GO:0005741 - mitochondrial outer membrane
GO:0005829 - cytosol
GO:0008630 - intrinsic apoptotic signaling pathway in response to DNA damage
and 6 others

more...

Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 204
Mm

1 233
+ Rn
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024