HitPredict

Interactor 1: KCNA4 (Q61423)
Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4)
Gene: KCNA4

Interactor 2: DLG4 (Q62108)
Disks large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP-90) (SAP90)
Gene: DLG4

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.82	0.60	0.705

Property	Details
Experiments	27507650, 28671696, 36604605, 19455133, 12067714
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, two hybrid array
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0008076 - voltage-gated potassium channel complex GO:0016020 - membrane GO:0043197 - dendritic spine GO:0045211 - postsynaptic membrane and 1 others more... GO:0098978 - glutamatergic synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 654 Mm			1 724
+	Rn
		548174 KCNA4_RAT (1-654): 0: 619: 98.93		DLG4_RAT (1-724): 0: 671: 99.45
+	Hs
		608221 KCNA4_HUMAN (1-654): 0: 602: 97.25		DLG4_HUMAN (1-724): 0: 671: 99.59
+	Rn
		548175 KCNA4_RAT (1-654): 0: 619: 98.93		DLG3_RAT (20-724): 0: 585: 63.94
+	Hs
		608244 KCNA4_HUMAN (1-654): 0: 602: 97.25		DLG3_HUMAN (28-724): 0: 600: 64.92
+	Hs
		608224 KCNA4_HUMAN (1-654): 0: 602: 97.25		DLG1_HUMAN (28-724): 0: 576: 72.79
+	Mm
		927733 KCNA2_MOUSE (154-654): 2.76e-156: 461: 66.67		DLG4_MOUSE (1-724): 0: 671: 100.00
+	Hs
		558713 KCNA2_HUMAN (153-654): 1.01e-155: 460: 66.53		DLG4_HUMAN (1-724): 0: 671: 99.59
+	Hs
		608268 KCNA5_HUMAN (53-630): 1.17e-151: 453: 54.81		DLG4_HUMAN (1-724): 0: 671: 99.59
+	Mm
		558878 KCNA3_MOUSE (160-654): 1.18e-149: 445: 68.14		DLG4_MOUSE (1-724): 0: 671: 100.00
+	Mm
		558703 KCNA1_MOUSE (146-654): 7.48e-150: 444: 65.17		DLG4_MOUSE (1-724): 0: 671: 100.00
+	Hs
		942333 KCNA1_HUMAN (146-654): 1.06e-149: 444: 64.78		DLG4_HUMAN (1-724): 0: 671: 99.59
+	Hs
		602901 KCNA3_HUMAN (83-654): 7.22e-148: 442: 60.79		DLG4_HUMAN (1-724): 0: 671: 99.59
+	Rn
		580271 KCNA5_RAT (69-632): 2.25e-158: 470: 57.54		DLG1_RAT (8-724): 0: 564: 66.98
+	Hs
		608272 KCNA5_HUMAN (53-630): 1.17e-151: 453: 54.81		DLG1_HUMAN (28-724): 0: 576: 72.79
+	Hs
		608230 KCNA4_HUMAN (1-654): 0: 602: 97.25		SCRIB_HUMAN (58-243): 7.53e-25: 113: 40.72
+	Hs
		159156 KCNA4_HUMAN (1-654): 0: 602: 97.25		CSKP_HUMAN (6-381): 1.53e-20: 99: 14.43
+	Hs
		608222 KCNA4_HUMAN (1-654): 0: 602: 97.25		EM55_HUMAN (6-265): 1.35e-19: 94.4: 15.71
+	Hs
		608231 KCNA4_HUMAN (1-654): 0: 602: 97.25		DLG2_HUMAN (234-580): 8.36e-18: 90.1: 19.55
+	Hs
		608232 KCNA4_HUMAN (1-654): 0: 602: 97.25		MPP7_HUMAN (51-193): 7.87e-16: 83.2: 16.08
+	Hs
		608277 KCNA5_HUMAN (53-630): 1.17e-151: 453: 54.81		SCRIB_HUMAN (58-243): 7.53e-25: 113: 40.72