Interactor 1: DLL1 (Q61483)
Delta-like protein 1 (Drosophila Delta homolog 1) (Delta1) [Cleaved into: Dll1-soluble form (Dll1-EC) (Shed form); Dll1-derived cell-associated form (Dll1-TMIC) (Membrane-associated fragment); Dll1-intracellular form (Dll1-IC)]
Gene: DLL1

Interactor 2: NEUL1 (Q923S6)
E3 ubiquitin-protein ligase NEURL1 (EC 2.3.2.27) (Neuralized-like protein 1A) (m-neu1) (m-neuralized 1) (Neuralized1) (RING-type E3 ubiquitin transferase NEURL1)
Gene: Neurl1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 19723503
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005886 - plasma membrane
GO:0007219 - Notch signaling pathway
GO:0008285 - negative regulation of cell population proliferation
GO:0045746 - negative regulation of Notch signaling pathway
Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 722
Mm

1 574
+ Hs
+ Mm
+ Mm
+ Dm
+ Dm
+ Dm
+ Dm
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024