HitPredict

Interactor 1: ERR2 (Q61539)
Steroid hormone receptor ERR2 (Estrogen receptor-like 2) (Estrogen-related receptor beta) (ERR-beta) (Nuclear receptor subfamily 3 group B member 2)
Gene: Esrrb

Interactor 2: RIF1 (Q6PR54)
Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog) (mRif1)
Gene: RIF1

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	20362541
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000793 - condensed chromosome GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0035019 - somatic stem cell population maintenance
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 433 Mm			1 2419
+	Hs
		369787 ESR1_HUMAN (10-432): 1.33e-111: 342: 33.05		RIF1_HUMAN (1-2419): 0: 1568: 67.72
+	Hs
		369851 ESR1_HUMAN (10-432): 1.33e-111: 342: 33.05		ANR11_HUMAN (951-2273): 5.66e-29: 130: 9.33
+	Hs
		369607 ESR1_HUMAN (10-432): 1.33e-111: 342: 33.05		MDC1_HUMAN (909-2090): 3.43e-22: 107: 7.78
+	Hs
		370263 ESR1_HUMAN (10-432): 1.33e-111: 342: 33.05		MINT_HUMAN (900-2398): 5.52e-18: 93.8: 8.87
+	Hs
		369909 ESR1_HUMAN (10-432): 1.33e-111: 342: 33.05		RBBP6_HUMAN (1488-2145): 1.71e-16: 88.9: 11.60
+	Hs
		782640 HNF4A_HUMAN (78-429): 2.37e-109: 332: 28.61		MINT_HUMAN (900-2398): 5.52e-18: 93.8: 8.87
+	Hs
		369815 ESR1_HUMAN (10-432): 1.33e-111: 342: 33.05		NIPBL_HUMAN (1421-2211): 2.08e-11: 72.3: 11.63
+	Hs
		369007 ESR1_HUMAN (10-432): 1.33e-111: 342: 33.05		APC_HUMAN (944-2181): 6.69e-11: 70.6: 8.83
+	Hs
		370105 ESR1_HUMAN (10-432): 1.33e-111: 342: 33.05		TITIN_HUMAN (818-1667): 3.09e-10: 68.4: 7.59
+	Hs
		782571 HNF4A_HUMAN (78-429): 2.37e-109: 332: 28.61		NIPBL_HUMAN (1421-2211): 2.08e-11: 72.3: 11.63
+	Hs
		1164769 ESR2_HUMAN (102-433): 1.13e-69: 231: 38.61		ANR11_HUMAN (951-2273): 5.66e-29: 130: 9.33
+	Hs
		1045396 ESR2_HUMAN (102-433): 1.13e-69: 231: 38.61		SHRM2_HUMAN (927-1868): 8.72e-23: 109: 10.00
+	Hs
		1056909 ESR2_HUMAN (102-433): 1.13e-69: 231: 38.61		MDC1_HUMAN (909-2090): 3.43e-22: 107: 7.78
+	Hs
		1270066 ESR2_HUMAN (102-433): 1.13e-69: 231: 38.61		PCLO_HUMAN (1020-2386): 2.4e-17: 91.8: 8.08
+	Hs
		1191700 ESR2_HUMAN (102-433): 1.13e-69: 231: 38.61		RBBP6_HUMAN (1488-2145): 1.71e-16: 88.9: 11.60
+	Hs
		1244235 ESR2_HUMAN (102-433): 1.13e-69: 231: 38.61		BD1L1_HUMAN (974-2043): 2.43e-16: 88.5: 10.87
+	Hs
		1154059 ESR2_HUMAN (102-433): 1.13e-69: 231: 38.61		NIPBL_HUMAN (1421-2211): 2.08e-11: 72.3: 11.63
+	Hs
		1264774 ESR2_HUMAN (102-433): 1.13e-69: 231: 38.61		TITIN_HUMAN (818-1667): 3.09e-10: 68.4: 7.59
+	Hs
		377401 GCR_HUMAN (99-352): 1.26e-45: 170: 37.98		NIPBL_HUMAN (1421-2211): 2.08e-11: 72.3: 11.63
+	Hs
		377537 GCR_HUMAN (99-352): 1.26e-45: 170: 37.98		MUC16_HUMAN (1079-2418): 5.94e-09: 64.1: 8.21