HitPredict

Interactor 1: FXR1 (Q61584)
RNA-binding protein FXR1 (FXR1P) (mFxr1p)
Gene: FXR1

Interactor 2: PRC2A (Q7TSC1)
Protein PRRC2A (HLA-B-associated transcript 2) (Proline-rich and coiled-coil-containing protein 2A)
Gene: Prrc2a

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	28671696
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 677 Mm			1 2158
+	Hs
		820851 FXR1_HUMAN (1-677): 0: 995: 88.33		PRC2A_HUMAN (1-2158): 2.68e-173: 587: 86.33
+	Hs
		820852 FXR2_HUMAN (4-656): 0: 851: 64.06		PRC2A_HUMAN (1-2158): 2.68e-173: 587: 86.33
+	Hs
		843719 FXR1_HUMAN (1-677): 0: 995: 88.33		PRC2B_HUMAN (1-2141): 2.62e-77: 288: 23.47
+	Mm
		1186751 Q8BPK8_MOUSE (1-334): 0: 622: 73.65		PRC2A_MOUSE (1-2158): 0: 646: 100.00
+	Mm
		1111986 FXR1_MOUSE (1-677): 0: 1073: 100.00		PRC2C_MOUSE (272-2157): 2.63e-20: 101: 9.36
+	Mm
		1142913 FXR1_MOUSE (1-677): 0: 1073: 100.00		NCOR2_MOUSE (896-2157): 8.74e-13: 76.5: 9.21
+	Mm
		1142852 FXR1_MOUSE (1-677): 0: 1073: 100.00		PRC2B_MOUSE (561-2020): 3.63e-10: 67.6: 9.93
+	Hs
		844097 FXR2_HUMAN (4-656): 0: 851: 64.06		PRC2B_HUMAN (1-2141): 2.62e-77: 288: 23.47
+	Hs
		843899 FXR1_HUMAN (1-677): 0: 995: 88.33		TARA_HUMAN (631-2037): 8.31e-25: 116: 11.20
+	Hs
		311796 FXR1_HUMAN (1-677): 0: 995: 88.33		TACC2_HUMAN (29-1370): 5.46e-14: 80.7: 9.76
+	Hs
		843980 FXR1_HUMAN (1-677): 0: 995: 88.33		PRC2C_HUMAN (294-2152): 2.19e-10: 68.8: 9.46
+	Hs
		844237 FXR2_HUMAN (4-656): 0: 851: 64.06		TARA_HUMAN (631-2037): 8.31e-25: 116: 11.20
+	Hs
		844303 FXR2_HUMAN (4-656): 0: 851: 64.06		PRC2C_HUMAN (294-2152): 2.19e-10: 68.8: 9.46
+	Mm
		729533 FMR1_MOUSE (219-461): 1.28e-49: 184: 42.80		PRC2A_MOUSE (1-2158): 0: 646: 100.00
+	Mm
		1111989 Q8BPK8_MOUSE (1-334): 0: 622: 73.65		PRC2C_MOUSE (272-2157): 2.63e-20: 101: 9.36
+	Mm
		1207112 Q8BPK8_MOUSE (1-334): 0: 622: 73.65		NCOR2_MOUSE (896-2157): 8.74e-13: 76.5: 9.21
+	Mm
		1186627 Q8BPK8_MOUSE (1-334): 0: 622: 73.65		PRC2B_MOUSE (561-2020): 3.63e-10: 67.6: 9.93
+	Mm
		729462 FMR1_MOUSE (219-461): 1.28e-49: 184: 42.80		PRC2C_MOUSE (272-2157): 2.63e-20: 101: 9.36
+	Mm
		729608 FMR1_MOUSE (219-461): 1.28e-49: 184: 42.80		NCOR2_MOUSE (896-2157): 8.74e-13: 76.5: 9.21
+	Mm
		729531 FMR1_MOUSE (219-461): 1.28e-49: 184: 42.80		PRC2B_MOUSE (561-2020): 3.63e-10: 67.6: 9.93