HitPredict

Interactor 1: FXR1 (Q61584)
RNA-binding protein FXR1 (FXR1P) (mFxr1p)
Gene: FXR1

Interactor 2: AGO1 (Q8CJG1)
Protein argonaute-1 (Argonaute1) (mAgo1) (Argonaute RISC catalytic component 1) (Eukaryotic translation initiation factor 2C 1) (eIF-2C 1) (eIF2C 1) (Piwi/argonaute family protein meIF2C1)
Gene: AGO1

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	28671696
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0036464 - cytoplasmic ribonucleoprotein granule GO:0043488 - regulation of mRNA stability
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 677 Mm			1 857
+	Mm
		1142880 FXR1_MOUSE (1-677): 0: 1073: 100.00		AGO2_MOUSE (3-857): 0: 1213: 82.36
+	Hs
		843957 FXR1_HUMAN (1-677): 0: 995: 88.33		AGO1_HUMAN (1-857): 0: 1222: 100.00
+	Hs
		843956 FXR1_HUMAN (1-677): 0: 995: 88.33		AGO2_HUMAN (19-857): 0: 1206: 83.43
+	Hs
		844281 FXR2_HUMAN (4-656): 0: 851: 64.06		AGO1_HUMAN (1-857): 0: 1222: 100.00
+	Hs
		844280 FXR2_HUMAN (4-656): 0: 851: 64.06		AGO2_HUMAN (19-857): 0: 1206: 83.43
+	Hs
		844248 FXR2_HUMAN (4-656): 0: 851: 64.06		AGO3_HUMAN (1-857): 0: 1189: 83.83
+	Mm
		1110532 Q3TA75_MOUSE (4-520): 0: 753: 67.18		AGO2_MOUSE (3-857): 0: 1213: 82.36
+	Mm
		1207064 Q8BPK8_MOUSE (1-334): 0: 622: 73.65		AGO1_MOUSE (1-857): 0: 1222: 100.00
+	Mm
		1207063 Q8BPK8_MOUSE (1-334): 0: 622: 73.65		AGO2_MOUSE (3-857): 0: 1213: 82.36
+	Dm
		1103827 FMR1_DROME (1-562): 0: 665: 41.03		Q32KD4_DROME (5-857): 0: 1153: 73.30
+	Mm
		729561 FMR1_MOUSE (219-461): 1.28e-49: 184: 42.80		AGO1_MOUSE (1-857): 0: 1222: 100.00
+	Hs
		989179 FMR1_HUMAN (300-461): 3.4e-48: 181: 56.10		AGO1_HUMAN (1-857): 0: 1222: 100.00
+	Mm
		729560 FMR1_MOUSE (219-461): 1.28e-49: 184: 42.80		AGO2_MOUSE (3-857): 0: 1213: 82.36
+	Hs
		989178 FMR1_HUMAN (300-461): 3.4e-48: 181: 56.10		AGO2_HUMAN (19-857): 0: 1206: 83.43
+	Dm
		1342058 FMR1_DROME (1-562): 0: 665: 41.03		AGO2_DROME (28-816): 0: 714: 32.09
+	Dm
		284349 FMR1_DROME (1-562): 0: 665: 41.03		AUB_DROME (2-815): 0: 596: 21.60