Interactor 1: GLI3 (Q61602)
Transcriptional activator GLI3 (GLI3 form of 190 kDa) (GLI3-190) (GLI3 full-length protein) (GLI3FL) [Cleaved into: Transcriptional repressor GLI3R (GLI3 C-terminally truncated form) (GLI3 form of 83 kDa) (GLI3-83)]
Gene: GLI3

Interactor 2: SUFU (Q9Z0P7)
Suppressor of fused homolog
Gene: SUFU

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 0.60 0.640

The method score is based on:

Property Details
Experiments 29515120, 20463034, 10531011
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005929 - cilium
and 8 others

more...

Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 1583
Mm

1 484
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Dm
+ Dm
+ Hs
+ Mm
+ Dr
+ Dr

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Last updated: 15 Jul 2024