HitPredict

Interactor 1: GRID2 (Q61625)
Glutamate receptor ionotropic, delta-2 (GluD2) (GluR delta-2 subunit)
Gene: GRID2

Interactor 2: DLG1 (Q811D0)
Disks large homolog 1 (Embryo-dlg/synapse-associated protein 97) (E-dlg/SAP97) (Synapse-associated protein 97) (SAP-97) (SAP97)
Gene: DLG1

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.60	0.457

Property	Details
Experiments	15207857
Identification Methods	two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0008104 - protein localization GO:0030165 - PDZ domain binding GO:0045202 - synapse GO:0098839 - postsynaptic density membrane and 1 others more... GO:0098978 - glutamatergic synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1007 Mm			1 905
+	Rn
		1144011 GRID2_RAT (1-1007): 0: 911: 99.50		DLG1_RAT (1-905): 0: 710: 95.83
+	Hs
		1021483 GRIK2_HUMAN (8-924): 0: 736: 26.72		DLG1_HUMAN (1-905): 0: 716: 95.58
+	Hs
		786696 GRIA1_HUMAN (6-889): 0: 726: 24.53		DLG1_HUMAN (1-905): 0: 716: 95.58
+	Rn
		585151 GRIA1_RAT (6-889): 0: 722: 24.64		DLG1_RAT (1-905): 0: 710: 95.83
+	Hs
		1022366 GRIK2_HUMAN (8-924): 0: 736: 26.72		DLG3_HUMAN (113-905): 0: 559: 65.14
+	Mm
		620881 GRIA1_MOUSE (6-889): 0: 719: 24.53		DLG3_MOUSE (113-905): 0: 551: 66.26
+	Mm
		1142961 GRID2_MOUSE (1-1007): 0: 912: 100.00		DLG4_MOUSE (32-431): 1.5e-31: 134: 16.50
+	Rn
		677792 GRID2_RAT (1-1007): 0: 911: 99.50		DLG4_RAT (32-431): 1.04e-30: 131: 16.50
+	Rn
		1144131 GRID2_RAT (1-1007): 0: 911: 99.50		DLG2_RAT (384-810): 4.74e-18: 91.4: 16.74
+	Mm
		1142983 GRID1_MOUSE (1-1007): 0: 785: 55.61		DLG4_MOUSE (32-431): 1.5e-31: 134: 16.50
+	Rn
		1143996 GRID1_RAT (1-1007): 0: 784: 55.71		DLG2_RAT (384-810): 4.74e-18: 91.4: 16.74
+	Mm
		761217 GRIK2_MOUSE (8-924): 0: 735: 26.61		DLG4_MOUSE (32-431): 1.5e-31: 134: 16.50
+	Hs
		942335 GRIK2_HUMAN (8-924): 0: 736: 26.72		DLG4_HUMAN (32-431): 5.87e-31: 132: 16.50
+	Rn
		677766 GRIK2_RAT (8-924): 0: 736: 26.61		DLG4_RAT (32-431): 1.04e-30: 131: 16.50
+	Hs
		761199 GRIK1_HUMAN (4-860): 0: 735: 27.75		DLG4_HUMAN (32-431): 5.87e-31: 132: 16.50
+	Rn
		585138 GRIA1_RAT (6-889): 0: 722: 24.64		DLG4_RAT (32-431): 1.04e-30: 131: 16.50
+	Mm
		620892 GRIA1_MOUSE (6-889): 0: 719: 24.53		DLG4_MOUSE (32-431): 1.5e-31: 134: 16.50
+	Mm
		1143566 GRIA3_MOUSE (6-871): 0: 702: 25.20		DLG4_MOUSE (32-431): 1.5e-31: 134: 16.50
+	Hs
		786757 GRIA3_HUMAN (6-871): 0: 703: 25.31		DLG4_HUMAN (32-431): 5.87e-31: 132: 16.50
+	Mm
		620904 GRIA1_MOUSE (6-889): 0: 719: 24.53		DLG2_MOUSE (384-810): 3.48e-18: 91.8: 16.74