HitPredict

Interactor 1: CBX5 (Q61686)
Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha)
Gene: CBX5

Interactor 2: H2B1B (Q64475)
Histone H2B type 1-B (H2B-clustered histone 3) (h2B-143)
Gene: H2bc3

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29795351
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 191 Mm			1 126
+	Hs
		800398 CBX5_HUMAN (1-191): 2.88e-69: 210: 97.91		H2B2E_HUMAN (1-126): 2.28e-54: 168: 96.03
+	Hs
		241469 CBX5_HUMAN (1-191): 2.88e-69: 210: 97.91		H2B1K_HUMAN (1-126): 4.91e-54: 167: 96.03
+	Hs
		800336 CBX5_HUMAN (1-191): 2.88e-69: 210: 97.91		H2B1C_HUMAN (1-126): 4.03e-54: 167: 96.83
+	Hs
		800460 CBX5_HUMAN (1-191): 2.88e-69: 210: 97.91		H2B3B_HUMAN (1-126): 4.53e-52: 162: 95.24
+	Hs
		1027018 CBX3_HUMAN (1-181): 4.97e-62: 192: 60.22		H2B2E_HUMAN (1-126): 2.28e-54: 168: 96.03
+	Hs
		241519 CBX3_HUMAN (1-181): 4.97e-62: 192: 60.22		H2B1K_HUMAN (1-126): 4.91e-54: 167: 96.03
+	Hs
		420833 CBX3_HUMAN (1-181): 4.97e-62: 192: 60.22		H2B1J_HUMAN (1-126): 2.63e-54: 167: 95.24
+	Hs
		918334 CBX3_HUMAN (1-181): 4.97e-62: 192: 60.22		H2B1C_HUMAN (1-126): 4.03e-54: 167: 96.83
+	Mm
		1145436 Q9DCC5_MOUSE (1-181): 4.97e-62: 192: 60.22		H2B1B_MOUSE (1-126): 1.3e-52: 163: 100.00
+	Hs
		949797 CBX1_HUMAN (26-180): 3.2e-56: 177: 64.74		H2B2E_HUMAN (1-126): 2.28e-54: 168: 96.03
+	Hs
		420825 CBX1_HUMAN (26-180): 3.2e-56: 177: 64.74		H2B1J_HUMAN (1-126): 2.63e-54: 167: 95.24
+	Hs
		707585 CBX1_HUMAN (26-180): 3.2e-56: 177: 64.74		H2B1B_HUMAN (1-126): 4.91e-54: 167: 97.62
+	Hs
		918291 CBX1_HUMAN (26-180): 3.2e-56: 177: 64.74		H2B1C_HUMAN (1-126): 4.03e-54: 167: 96.83
+	Mm
		949938 CBX1_MOUSE (26-180): 3.2e-56: 177: 64.74		H2B1B_MOUSE (1-126): 1.3e-52: 163: 100.00
+	Hs
		203602 SUV91_HUMAN (4-120): 2.31e-34: 127: 20.51		H2B1K_HUMAN (1-126): 4.91e-54: 167: 96.03
+	Hs
		1087494 CDYL_HUMAN (8-159): 2.83e-30: 117: 23.13		H2B2E_HUMAN (1-126): 2.28e-54: 168: 96.03
+	Hs
		918778 CDYL_HUMAN (8-159): 2.83e-30: 117: 23.13		H2B1C_HUMAN (1-126): 4.03e-54: 167: 96.83
+	Hs
		1231263 CDYL_HUMAN (8-159): 2.83e-30: 117: 23.13		H2B3B_HUMAN (1-126): 4.53e-52: 162: 95.24
+	Hs
		123191 CBX4_HUMAN (11-125): 2.1e-27: 109: 25.22		H2B1B_HUMAN (1-126): 4.91e-54: 167: 97.62
+	Hs
		1282983 CDYL_HUMAN (8-159): 2.83e-30: 117: 23.13		H2B1A_HUMAN (1-126): 2.02e-46: 148: 85.04