Interactor 1: PEA15 (Q62048)
Astrocytic phosphoprotein PEA-15 (15 kDa phosphoprotein enriched in astrocytes)
Gene: PEA15

Interactor 2: MK03 (Q63844)
Mitogen-activated protein kinase 3 (MAP kinase 3) (MAPK 3) (EC 2.7.11.24) (ERT2) (Extracellular signal-regulated kinase 1) (ERK-1) (Insulin-stimulated MAP2 kinase) (MAP kinase isoform p44) (p44-MAPK) (MNK1) (Microtubule-associated protein 2 kinase) (p44-ERK1)
Gene: Mapk3

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.52 1.00 0.724

The method score is based on:

Property Details
Experiments 15537391
Identification Methods affinity chromatography technology, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains DED~Pkinase
Common GO terms GO:0000165 - MAPK cascade
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0006915 - apoptotic process
GO:0035556 - intracellular signal transduction
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 130
Mm

1 380
+ Hs
+ Rn
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024