Interactor 1: M3K7 (Q62073)
Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1)
Gene: Map3k7
Interactor 2: TGFR1 (Q64729)
TGF-beta receptor type-1 (TGFR-1) (EC 2.7.11.30) (ESK2) (Transforming growth factor-beta receptor type I) (TGF-beta receptor type I) (TbetaR-I)
Gene: Tgfbr1
Species: Mus musculus
Source: innatedb
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 19556242 |
| Identification Methods | anti tag coimmunoprecipitation |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | PK_Tyr_Ser-Thr~Pkinase, PK_Tyr_Ser-Thr~TGF_beta_GS |
| Common GO terms | GO:0001525 - angiogenesis GO:0004674 - protein serine/threonine kinase activity GO:0005114 - type II transforming growth factor beta receptor binding GO:0005524 - ATP binding GO:0005886 - plasma membrane and 3 others more... |
| Homologous interactions | 15 |
Homologous interactions
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Last updated: 15 Jul 2024
