HitPredict

Interactor 1: DLG4 (Q62108)
Disks large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP-90) (SAP90)
Gene: DLG4

Interactor 2: ABTB3 (Q6GQW0)
Ankyrin repeat and BTB/POZ domain-containing protein 3 (BTB/POZ domain-containing protein 11)
Gene: ABTB3

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.70	1.00	0.839

Property	Details
Experiments	28671696, 36604605, 19455133
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Ank_2~SH3_1
Common GO terms	GO:0016020 - membrane GO:0030165 - PDZ domain binding GO:0098978 - glutamatergic synapse
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 724 Mm			1 1109
+	Mm
		103602 DLG4_MOUSE (1-724): 0: 671: 100.00		ANK3_MOUSE (233-819): 1.55e-85: 307: 15.07
+	Mm
		1143421 DLG4_MOUSE (1-724): 0: 671: 100.00		ANK2_MOUSE (233-755): 2.2e-77: 283: 14.33
+	Dm
		677732 DLG1_DROME (22-322): 5.59e-26: 116: 20.79		Q9W2I0_DROME (626-983): 2.2e-35: 148: 14.17
+	Hs
		1021434 DLG5_HUMAN (40-245): 4.01e-17: 88.6: 31.55		ANK3_HUMAN (225-595): 2.31e-36: 152: 10.85
+	Hs
		958815 EM55_HUMAN (6-265): 1.35e-19: 94.4: 15.71		KLH12_HUMAN (906-1086): 4.32e-33: 137: 20.88
+	Hs
		1050092 SCRIB_HUMAN (58-243): 7.53e-25: 113: 40.72		ANR50_HUMAN (669-1009): 1.51e-21: 103: 14.45