HitPredict

Interactor 1: DLG4 (Q62108)
Disks large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP-90) (SAP90)
Gene: DLG4

Interactor 2: KCC2D (Q6PHZ2)
Calcium/calmodulin-dependent protein kinase type II subunit delta (CaM kinase II subunit delta) (CaMK-II subunit delta) (EC 2.7.11.17)
Gene: Camk2d

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.60	0.650

Property	Details
Experiments	27507650, 28671696, 19455133
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0031594 - neuromuscular junction GO:0043005 - neuron projection
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 724 Mm			1 499
+	Mm
		515234 DLG4_MOUSE (1-724): 0: 671: 100.00		KCC2A_MOUSE (1-474): 0: 542: 87.58
+	Mm
		1131547 DLG4_MOUSE (1-724): 0: 671: 100.00		Q5SVI3_MOUSE (1-478): 0: 540: 80.31
+	Hs
		1271040 DLG3_HUMAN (28-724): 0: 600: 64.92		KCC2A_HUMAN (1-474): 0: 541: 87.37
+	Rn
		506744 DLG3_RAT (20-724): 0: 585: 63.94		KCC2A_RAT (1-474): 0: 542: 87.58
+	Hs
		1021591 DLG1_HUMAN (28-724): 0: 576: 72.79		KCC2A_HUMAN (1-474): 0: 541: 87.37
+	Rn
		506740 DLG1_RAT (8-724): 0: 564: 66.98		KCC2A_RAT (1-474): 0: 542: 87.58
+	Hs
		159190 DLG4_HUMAN (1-724): 0: 671: 99.59		CSKP_HUMAN (10-308): 1.58e-88: 292: 47.71
+	Hs
		159249 DLG3_HUMAN (28-724): 0: 600: 64.92		CSKP_HUMAN (10-308): 1.58e-88: 292: 47.71
+	Mm
		251104 DLG1_MOUSE (8-724): 0: 577: 68.93		CSKP_MOUSE (10-308): 1.58e-88: 292: 47.71
+	Hs
		159200 DLG1_HUMAN (28-724): 0: 576: 72.79		CSKP_HUMAN (10-308): 1.58e-88: 292: 47.71
+	Rn
		1144009 DLG1_RAT (8-724): 0: 564: 66.98		CSKP_RAT (10-308): 1.2e-88: 292: 47.71
+	Mm
		659457 DLG4_MOUSE (1-724): 0: 671: 100.00		KCC2B_MOUSE (321-478): 1.32e-51: 185: 79.75
+	Dm
		677687 DLG1_DROME (22-322): 5.59e-26: 116: 20.79		KCC2A_DROME (1-472): 1.19e-178: 513: 74.56
+	Dm
		959117 CSKP_DROME (34-161): 1.19e-13: 76.7: 14.73		KCC2A_DROME (1-472): 1.19e-178: 513: 74.56
+	Hs
		159110 CSKP_HUMAN (6-381): 1.53e-20: 99: 14.43		CSKP_HUMAN (10-308): 1.58e-88: 292: 47.71