HitPredict

Interactor 1: DLG4 (Q62108)
Disks large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP-90) (SAP90)
Gene: DLG4

Interactor 2: LRFN2 (Q80TG9)
Leucine-rich repeat and fibronectin type-III domain-containing protein 2
Gene: LRFN2

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.866

Property	Details
Experiments	16828986, 28604739, 16495444
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	PDZ~fn3
Common GO terms	GO:0098794 - postsynapse GO:0098839 - postsynaptic density membrane
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 724 Mm			1 788
+	Rn
		677783 DLG4_RAT (1-724): 0: 671: 99.45		LRFN2_RAT (1-788): 1.53e-165: 500: 98.86
+	Rn
		1115172 DLG3_RAT (20-724): 0: 585: 63.94		LRFN2_RAT (1-788): 1.53e-165: 500: 98.86
+	Mm
		936183 DLG3_MOUSE (20-724): 0: 585: 63.94		LRFN2_MOUSE (1-788): 1.04e-164: 498: 100.00
+	Mm
		1193431 DLG1_MOUSE (8-724): 0: 577: 68.93		LRFN2_MOUSE (1-788): 1.04e-164: 498: 100.00
+	Rn
		1115171 DLG1_RAT (8-724): 0: 564: 66.98		LRFN2_RAT (1-788): 1.53e-165: 500: 98.86
+	Mm
		1103492 DLG4_MOUSE (1-724): 0: 671: 100.00		LRFN1_MOUSE (12-788): 4.1e-119: 378: 44.68
+	Mm
		1103493 DLG1_MOUSE (8-724): 0: 577: 68.93		LRFN1_MOUSE (12-788): 4.1e-119: 378: 44.68
+	Mm
		1143410 DLG4_MOUSE (1-724): 0: 671: 100.00		LRC4C_MOUSE (17-449): 2.01e-66: 234: 22.41
+	Mm
		936185 DLG3_MOUSE (20-724): 0: 585: 63.94		LRC4C_MOUSE (17-449): 2.01e-66: 234: 22.41
+	Mm
		1143386 DLG4_MOUSE (1-724): 0: 671: 100.00		NRCAM_MOUSE (133-779): 7.85e-29: 126: 12.32
+	Mm
		471547 DLG4_MOUSE (1-724): 0: 671: 100.00		LRC4B_MOUSE (5-223): 8.39e-25: 112: 20.18
+	Mm
		1143377 DLG4_MOUSE (1-724): 0: 671: 100.00		LRFN4_MOUSE (6-126): 3.19e-13: 75.1: 18.32
+	Mm
		1195001 DLG1_MOUSE (8-724): 0: 577: 68.93		NRCAM_MOUSE (133-779): 7.85e-29: 126: 12.32
+	Mm
		1207544 DLG2_MOUSE (234-473): 4.91e-17: 87.8: 21.95		LRC4C_MOUSE (17-449): 2.01e-66: 234: 22.41
+	Hs
		1050047 SCRIB_HUMAN (58-243): 7.53e-25: 113: 40.72		LGR4_HUMAN (26-318): 8.01e-31: 132: 16.36
+	Hs
		1050029 SCRIB_HUMAN (58-243): 7.53e-25: 113: 40.72		LRIG1_HUMAN (35-519): 3.58e-29: 127: 13.08
+	Hs
		1162226 PALS1_HUMAN (22-196): 1.91e-13: 75.9: 14.21		LRFN4_HUMAN (6-126): 9.02e-14: 77: 17.56