HitPredict

Interactor 1: DLG4 (Q62108)
Disks large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP-90) (SAP90)
Gene: DLG4

Interactor 2: NETO1 (Q8R4I7)
Neuropilin and tolloid-like protein 1 (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1)
Gene: NETO1

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.85	0.60	0.716

The method score is based on:

Property	Details
Experiments	27507650, 28671696, 36604605, 19243221, 19455133
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, two hybrid, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0014069 - postsynaptic density GO:0035255 - ionotropic glutamate receptor binding GO:0045202 - synapse GO:0048169 - regulation of long-term neuronal synaptic plasticity GO:0060076 - excitatory synapse and 5 others more... GO:0097120 - receptor localization to synapse GO:0098839 - postsynaptic density membrane GO:0098978 - glutamatergic synapse GO:0099645 - neurotransmitter receptor localization to postsynaptic specialization membrane GO:2000463 - positive regulation of excitatory postsynaptic potential
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1	724
Mm

1	533

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024