HitPredict

Interactor 1: DLG4 (Q62108)
Disks large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP-90) (SAP90)
Gene: DLG4

Interactor 2: DLG2 (Q91XM9)
Disks large homolog 2 (Channel-associated protein of synapse-110) (Chapsyn-110) (Postsynaptic density protein PSD-93)
Gene: DLG2

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.84 1.00 0.922

The method score is based on:

Property Details
Experiments 27507650, 28671696, 36417873, 36604605, 19455133
Identification Methods affinity chromatography technology, proximity labelling technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Guanylate_kin~Guanylate_kin, Guanylate_kin~PDZ, Guanylate_kin~SH3_1, PDZ~PDZ, SH3_1~SH3_1
Common GO terms GO:0007268 - chemical synaptic transmission
GO:0008076 - voltage-gated potassium channel complex
GO:0009790 - embryo development
GO:0014069 - postsynaptic density
GO:0016020 - membrane
and 19 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 724
Mm

1 852
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024