HitPredict

Interactor 1: DLG4 (Q62108)
Disks large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP-90) (SAP90)
Gene: DLG4

Interactor 2: LRP8 (Q924X6)
Low-density lipoprotein receptor-related protein 8 (LRP-8) (Apolipoprotein E receptor 2)
Gene: LRP8

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	16332682
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0007268 - chemical synaptic transmission GO:0019894 - kinesin binding GO:0030425 - dendrite GO:0045202 - synapse
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 724 Mm			1 996
+	Hs
		942339 DLG4_HUMAN (1-724): 0: 671: 99.59		LRP8_HUMAN (4-266): 2.83e-24: 111: 28.26
+	Mm
		69882 DLG4_MOUSE (1-724): 0: 671: 100.00		B1AXJ3_MOUSE (4-161): 1.48e-12: 73.7: 16.67
+	Mm
		57555 DLG4_MOUSE (1-724): 0: 671: 100.00		LRP2_MOUSE (716-932): 1.76e-09: 64.5: 13.55
+	Hs
		942331 DLG4_HUMAN (1-724): 0: 671: 99.59		LRP1_HUMAN (62-337): 2.4e-09: 63.7: 14.19
+	Hs
		942324 DLG4_HUMAN (1-724): 0: 671: 99.59		LRP2_HUMAN (725-932): 4.49e-09: 62.9: 11.81
+	Mm
		1143471 DLG4_MOUSE (1-724): 0: 671: 100.00		LRP1_MOUSE (78-241): 6.84e-09: 62.6: 26.90
+	Hs
		957631 DLG3_HUMAN (28-724): 0: 600: 64.92		LRP2_HUMAN (725-932): 4.49e-09: 62.9: 11.81
+	Hs
		957608 DLG2_HUMAN (234-580): 8.36e-18: 90.1: 19.55		LRP2_HUMAN (725-932): 4.49e-09: 62.9: 11.81