HitPredict

Interactor 1: DLG4 (Q62108)
Disks large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP-90) (SAP90)
Gene: DLG4

Interactor 2: ADA22 (Q9R1V6)
Disintegrin and metalloproteinase domain-containing protein 22 (ADAM 22)
Gene: Adam22

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.86 0.60 0.722

The method score is based on:

Property Details
Experiments 27507650, 28671696, 36417873, 36604605, 19455133, 19022416
Identification Methods affinity chromatography technology, proximity labelling technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0016020 - membrane
GO:0098839 - postsynaptic density membrane
GO:0098978 - glutamatergic synapse
GO:0099645 - neurotransmitter receptor localization to postsynaptic specialization membrane
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 724
Mm

1 904
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Mm
+ Dm
+ Hs
+ Hs

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Last updated: 15 Jul 2024