HitPredict

Interactor 1: DLG4 (Q62108)
Disks large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP-90) (SAP90)
Gene: DLG4

Interactor 2: KS6A2 (Q9WUT3)
Ribosomal protein S6 kinase alpha-2 (S6K-alpha-2) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (p90RSK2) (MAP kinase-activated protein kinase 1c) (MAPK-activated protein kinase 1c) (MAPKAP kinase 1c) (MAPKAPK-1c) (Protein-tyrosine kinase Mpk-9) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3)
Gene: Rps6ka2

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36604605
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 724 Mm			1 733
+	Hs
		942348 DLG4_HUMAN (1-724): 0: 671: 99.59		KS6A1_HUMAN (20-733): 0: 793: 79.55
+	Hs
		1021498 DLG1_HUMAN (28-724): 0: 576: 72.79		KS6A2_HUMAN (1-733): 0: 820: 95.63
+	Mm
		554913 DLG4_MOUSE (1-724): 0: 671: 100.00		KPCE_MOUSE (319-721): 9.33e-101: 327: 22.91
+	Hs
		1049957 SCRIB_HUMAN (58-243): 7.53e-25: 113: 40.72		KS6A2_HUMAN (1-733): 0: 820: 95.63
+	Hs
		958810 EM55_HUMAN (6-265): 1.35e-19: 94.4: 15.71		KS6A2_HUMAN (1-733): 0: 820: 95.63
+	Hs
		850651 SCRIB_HUMAN (58-243): 7.53e-25: 113: 40.72		KS6A3_HUMAN (7-733): 0: 794: 80.36
+	Hs
		1049960 SCRIB_HUMAN (58-243): 7.53e-25: 113: 40.72		KS6A1_HUMAN (20-733): 0: 793: 79.55
+	Hs
		1071647 MPP7_HUMAN (51-193): 7.87e-16: 83.2: 16.08		KS6A2_HUMAN (1-733): 0: 820: 95.63
+	Hs
		958811 EM55_HUMAN (6-265): 1.35e-19: 94.4: 15.71		KS6A1_HUMAN (20-733): 0: 793: 79.55
+	Hs
		958860 EM55_HUMAN (6-265): 1.35e-19: 94.4: 15.71		KS6A6_HUMAN (21-733): 0: 760: 75.63