HitPredict

Interactor 1: DLG4 (Q62108)
Disks large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP-90) (SAP90)
Gene: DLG4

Interactor 2: MPP2 (Q9WV34)
MAGUK p55 subfamily member 2 (Discs large homolog 2) (Protein MPP2)
Gene: MPP2

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.789

The method score is based on:

Property Details
Experiments 27507650, 28671696
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Guanylate_kin~Guanylate_kin, Guanylate_kin~PDZ, Guanylate_kin~SH3_2, PDZ~PDZ, PDZ~SH3_2, Guanylate_kin~SH3_1, SH3_1~SH3_2
Common GO terms GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0005911 - cell-cell junction
GO:0014069 - postsynaptic density
GO:0030165 - PDZ domain binding
and 4 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 724
Mm

1 552
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024