Interactor 1: RAGE (Q62151)
Advanced glycosylation end product-specific receptor (Receptor for advanced glycosylation end products)
Gene: Ager

Interactor 2: TIRAP (Q99JY1)
Toll/interleukin-1 receptor domain-containing adapter protein (TIR domain-containing adapter protein) (Adaptor protein Wyatt) (MyD88 adapter-like protein)
Gene: TIRAP

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.33 0.60 0.445

The method score is based on:

Property Details
Experiments 21829704
Identification Methods anti bait coimmunoprecipitation
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005886 - plasma membrane
GO:0006954 - inflammatory response
GO:0032735 - positive regulation of interleukin-12 production
GO:0032755 - positive regulation of interleukin-6 production
GO:0032760 - positive regulation of tumor necrosis factor production
and 2 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 402
Mm

1 241
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024