HitPredict

Interactor 1: TRI27 (Q62158)
Zinc finger protein RFP (EC 2.3.2.27) (Ret finger protein) (Tripartite motif-containing protein 27)
Gene: Trim27

Interactor 2: TBK1 (Q9WUN2)
Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (T2K) (TANK-binding kinase 1)
Gene: TBK1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34646390
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0045087 - innate immune response
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 513 Mm			1 729
+	Hs
		537119 TRI27_HUMAN (1-513): 0: 520: 98.83		TBK1_HUMAN (1-729): 0: 562: 94.10
+	Hs
		585090 RO52_HUMAN (1-500): 4.54e-158: 459: 37.18		TBK1_HUMAN (1-729): 0: 562: 94.10
+	Hs
		536827 TRI27_HUMAN (1-513): 0: 520: 98.83		IKKE_HUMAN (1-715): 7.37e-150: 455: 48.54
+	Hs
		1318703 TRIM7_HUMAN (11-481): 8.6e-132: 394: 38.62		TBK1_HUMAN (1-729): 0: 562: 94.10
+	Hs
		1354523 TRI10_HUMAN (1-482): 9.62e-125: 374: 34.43		TBK1_HUMAN (1-729): 0: 562: 94.10
+	Hs
		158386 TRI27_HUMAN (1-513): 0: 520: 98.83		IKKB_HUMAN (9-709): 4.06e-128: 400: 18.63
+	Hs
		167459 TRI27_HUMAN (1-513): 0: 520: 98.83		IKKA_HUMAN (9-643): 5.48e-119: 375: 20.53
+	Hs
		158392 RO52_HUMAN (1-500): 4.54e-158: 459: 37.18		IKKB_HUMAN (9-709): 4.06e-128: 400: 18.63
+	Hs
		1050263 TRIM7_HUMAN (11-481): 8.6e-132: 394: 38.62		IKKE_HUMAN (1-715): 7.37e-150: 455: 48.54
+	Hs
		1050264 TRIM6_HUMAN (1-494): 5.98e-132: 393: 32.03		IKKE_HUMAN (1-715): 7.37e-150: 455: 48.54
+	Hs
		584875 RO52_HUMAN (1-500): 4.54e-158: 459: 37.18		CDK2_HUMAN (6-312): 9.48e-120: 362: 20.97
+	Hs
		167580 TRI22_HUMAN (1-494): 2.77e-131: 392: 29.31		IKKA_HUMAN (9-643): 5.48e-119: 375: 20.53
+	Hs
		1290895 TRI11_HUMAN (1-500): 2.64e-146: 429: 38.20		MARK1_HUMAN (9-407): 3.57e-86: 290: 24.57
+	Hs
		1357714 TRI35_HUMAN (3-492): 1.22e-102: 318: 26.65		MRCKB_HUMAN (6-715): 1.84e-111: 372: 17.21
+	Mm
		250797 TRI27_MOUSE (1-513): 0: 522: 100.00		ULK1_MOUSE (13-222): 6.31e-26: 116: 33.64
+	Hs
		262230 TRI27_HUMAN (1-513): 0: 520: 98.83		ULK1_HUMAN (13-222): 3.4e-26: 117: 34.10
+	Hs
		262235 RO52_HUMAN (1-500): 4.54e-158: 459: 37.18		ULK1_HUMAN (13-222): 3.4e-26: 117: 34.10
+	Hs
		1318781 TRI39_HUMAN (7-494): 3.45e-154: 451: 37.20		DCLK3_HUMAN (14-238): 8.02e-23: 105: 30.22
+	Hs
		883160 TRI68_HUMAN (1-496): 4.48e-143: 421: 34.38		HUNK_HUMAN (15-224): 2.85e-21: 100: 33.95
+	Hs
		183318 MEFV_HUMAN (17-496): 5.68e-128: 393: 36.63		ULK1_HUMAN (13-222): 3.4e-26: 117: 34.10