HitPredict

Interactor 1: TGFI1 (Q62219)
Transforming growth factor beta-1-induced transcript 1 protein (Androgen receptor-associated protein of 55 kDa) (Hydrogen peroxide-inducible clone 5 protein) (Hic-5) (TGF beta-stimulated clone 5) (TSC-5)
Gene: Tgfb1i1

Interactor 2: GIT1 (Q68FF6)
ARF GTPase-activating protein GIT1 (ARF GAP GIT1) (G protein-coupled receptor kinase-interactor 1) (GRK-interacting protein 1)
Gene: GIT1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.50	1.00	0.713

Property	Details
Experiments	12153727
Identification Methods	two hybrid, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Ank_2~LIM
Common GO terms	GO:0005829 - cytosol GO:0005925 - focal adhesion GO:0046872 - metal ion binding
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 461 Mm			1 770
+	Hs
		200193 TGFI1_HUMAN (1-461): 3.26e-98: 304: 91.32		GIT1_HUMAN (1-770): 3.24e-162: 490: 96.36
+	Mm
		1148430 PAXI_MOUSE (345-461): 3.63e-36: 142: 33.33		GIT1_MOUSE (1-770): 1.02e-164: 497: 100.00
+	Hs
		823519 PAXI_HUMAN (345-461): 1.43e-36: 143: 33.33		GIT1_HUMAN (1-770): 3.24e-162: 490: 96.36
+	Hs
		823392 PAXI_HUMAN (345-461): 1.43e-36: 143: 33.33		GIT2_HUMAN (1-768): 1.45e-139: 431: 63.71
+	Hs
		239000 LPXN_HUMAN (203-284): 3.63e-12: 69.5: 29.27		GIT1_HUMAN (1-770): 3.24e-162: 490: 96.36
+	Hs
		238962 LPXN_HUMAN (203-284): 3.63e-12: 69.5: 29.27		GIT2_HUMAN (1-768): 1.45e-139: 431: 63.71
+	Hs
		1176238 ZN534_HUMAN (198-461): 2.68e-57: 202: 11.83		AGAP1_HUMAN (2-236): 4.18e-55: 205: 31.93
+	Hs
		67874 ZN724_HUMAN (13-227): 3.79e-57: 200: 6.02		AN36B_HUMAN (114-766): 1.92e-50: 193: 12.13
+	Hs
		823513 PAXI_HUMAN (345-461): 1.43e-36: 143: 33.33		ASAP1_HUMAN (2-652): 2.37e-55: 208: 14.72
+	Hs
		195789 PAXI_HUMAN (345-461): 1.43e-36: 143: 33.33		ASAP2_HUMAN (2-543): 2.91e-50: 192: 16.26
+	Hs
		977972 ZNF92_HUMAN (75-272): 1.08e-18: 90.6: 5.53		AN36B_HUMAN (114-766): 1.92e-50: 193: 12.13
+	Dm
		54849 ZASP_DROME (344-460): 9.34e-11: 66.6: 31.93		CEG1A_DROME (1-213): 3.46e-56: 210: 28.70
+	Hs
		965107 ZYX_HUMAN (344-461): 1.1e-21: 99: 35.54		ANK2_HUMAN (89-573): 7.15e-31: 133: 11.72
+	Hs
		1080788 ZYX_HUMAN (344-461): 1.1e-21: 99: 35.54		TANC2_HUMAN (179-479): 2.76e-15: 82.6: 11.18
+	Hs
		1044709 FHL3_HUMAN (250-461): 3.76e-20: 92: 27.32		TANC2_HUMAN (179-479): 2.76e-15: 82.6: 11.18
+	Hs
		549241 ZN250_HUMAN (46-248): 1.57e-19: 93.3: 8.37		ANR50_HUMAN (213-528): 8.62e-15: 81: 10.94