Interactor 1: SHH (Q62226)
Sonic hedgehog protein (SHH) (EC 3.1.-.-) (HHG-1) (Shh unprocessed N-terminal signaling and C-terminal autoprocessing domains) (ShhNC) [Cleaved into: Sonic hedgehog protein N-product (ShhN) (Shh N-terminal processed signaling domains) (ShhNp) (Sonic hedgehog protein 19 kDa product)]
Gene: SHH

Interactor 2: HHIP (Q7TN16)
Hedgehog-interacting protein (HHIP) (HIP)
Gene: HHIP

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 10050855
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains GSDH~HH_signal
Common GO terms GO:0005576 - extracellular region
GO:0005886 - plasma membrane
GO:0007165 - signal transduction
GO:0007405 - neuroblast proliferation
GO:0008270 - zinc ion binding
and 4 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 437
Mm

1 700
+ Hs
+ Hs
+ Hs
+ Dm

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Last updated: 15 Jul 2024