HitPredict

Interactor 1: TGFR2 (Q62312)
TGF-beta receptor type-2 (TGFR-2) (EC 2.7.11.30) (TGF-beta type II receptor) (Transforming growth factor-beta receptor type II) (TGF-beta receptor type II) (TbetaR-II)
Gene: Tgfbr2

Interactor 2: AP2B1 (Q9DBG3)
AP-2 complex subunit beta (AP105B) (Adaptor protein complex AP-2 subunit beta) (Adaptor-related protein complex 2 subunit beta) (Beta-2-adaptin) (Beta-adaptin) (Clathrin assembly protein complex 2 beta large chain) (Plasma membrane adaptor HA2/AP2 adaptin beta subunit)
Gene: AP2B1

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24319055
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007507 - heart development
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 567 Mm			1 937
+	Hs
		739946 TGFR2_HUMAN (1-567): 6.41e-150: 444: 92.24		AP2B1_HUMAN (1-937): 0: 924: 99.89
+	Hs
		738326 BMR1A_HUMAN (32-548): 8.33e-120: 365: 27.05		AP2B1_HUMAN (1-937): 0: 924: 99.89
+	Mm
		1145507 TGFR1_MOUSE (43-545): 1.11e-119: 364: 30.50		AP2B1_MOUSE (1-937): 0: 924: 100.00
+	Hs
		738522 TGFR1_HUMAN (49-545): 2.03e-115: 353: 31.06		AP2B1_HUMAN (1-937): 0: 924: 99.89
+	Dm
		52543 A1Z7L8_DROME (41-549): 1.37e-121: 373: 27.05		Q24253_DROME (1-937): 0: 801: 71.64
+	Dm
		1096901 Q7YU60_DROME (41-549): 2.99e-121: 371: 27.98		Q24253_DROME (1-937): 0: 801: 71.64
+	Hs
		321501 BMR1A_HUMAN (32-548): 8.33e-120: 365: 27.05		AP2A1_HUMAN (11-932): 0: 634: 16.77
+	At
		1352915 BRL2_ARATH (5-144): 2.21e-16: 85: 9.46		COPB2_ARATH (6-919): 0: 579: 13.74